NAD+ 500mg

Researchers investigate cellular energy pathway using NAD+ in experimental models. Cellular energy pathways are sequences of molecular reactions that produce cellular fuel. Laboratory teams explore redox balance studies in controlled research settings. Redox balance refers to the equilibrium between oxidation and reduction reactions. Scientists conduct controlled experimental compound stability research under various conditions. Compound stability research investigates how molecules maintain structure over time. These studies occur exclusively in research environments without clinical applications.

NAD+ is investigated in research environments for cellular pathway analysis. Scientists have studied this compound within controlled laboratory models using standardized protocols. The formulation is explored for experimental cellular research in academic facilities. Researchers evaluate the compound under controlled conditions without outcome claims.

Store NAD+ in cool, dry, light-protected conditions between 2-8°C. Light-protected storage means keeping containers away from direct sunlight and bright lights. This product is intended for laboratory handling only by qualified research personnel. Qualified personnel have received training in compound reconstitution and handling techniques. Avoid moisture exposure as water content can affect compound stability and purity. Avoid heat exposure above recommended temperature ranges to maintain structural integrity. Structural integrity refers to compounds maintaining their proper molecular configuration. Reconstituted solutions should follow established laboratory storage guidelines for compound research protocols.

Each NAD+ batch undergoes comprehensive purity verification procedures through analytical methods. Analytical methods use scientific instruments to measure compound composition and quality. Our processes ensure batch-to-batch consistency across all research supply orders. Internal quality assurance standards follow research-grade supply positioning for laboratory compounds. Research-grade supply indicates products meet specifications for scientific laboratory use. Testing protocols verify compound purity and structural characteristics using validated techniques. Every unit meets our specifications before receiving distribution approval. Laboratory certificates accompany each order for institutional tracking and compliance documentation.

• CAS: 53-84-9
• Chemical Formula: C₂₁H₂₇N₇O₁₄P₂
• Molecular Weight: 663.43 g/mol
• Synonyms: Nicotinamide adenine dinucleotide, nmn, nad
• Shelf life: 24 months from the manufacturing date.

NAD+ is a cellular cofactor present in all living cells studied in research. Cofactors are molecules that assist enzymes in carrying out chemical reactions. The compound consists of two nucleotides joined through phosphate groups. Nucleotides are molecular building blocks composed of sugar, phosphate, and nitrogen bases. Cellular cofactors are studied in research to understand fundamental energy processes. Energy processes describe how cells convert nutrients into usable cellular fuel. The general role of NAD+ in laboratory research models includes serving as electron carrier. Electron carriers transport electrons during oxidation-reduction reactions. Researchers investigate how this cofactor participates in various metabolic pathways. Metabolic pathways are series of chemical reactions occurring in laboratory cell models.

NAD+ provides a research-grade compound formulation developed for scientific applications. Research-grade formulations meet quality standards required for laboratory use. Each batch undergoes high-purity testing to ensure consistency across research orders. The compound is designed for controlled laboratory environments conducting cellular research. Cellular research examines molecular processes within cell-based experimental systems. Secure packaging with discreet shipment protects the compound during transit to research facilities.

Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme in cellular metabolism, serving as an electron carrier in oxidative phosphorylation and as a substrate for NAD+-dependent enzymes including sirtuins (SIRT1-7), poly-ADP-ribose polymerases (PARPs), and CD38 NADase. In biochemical research, NAD+ is used to reconstitute enzymatic activity in cell-free systems, as a substrate for sirtuin deacylase assays, and as a reagent in metabolic research programmes investigating NAD+ homeostasis.

NAD+ is the obligate substrate for sirtuin deacetylase reactions, where it is cleaved to yield nicotinamide and 2′-O-acetyl-ADP-ribose. PARP1 and related PARPs use NAD+ to synthesise poly-ADP-ribose chains on target proteins during DNA damage responses. Alcohol dehydrogenase, lactate dehydrogenase, and many mitochondrial dehydrogenases use NAD+ as a hydride acceptor. In research, cycling assay systems using alcohol dehydrogenase and diaphorase allow sensitive quantification of NAD+ in cell and tissue samples.

Declining NAD+ levels with age have been documented across multiple organisms and tissue types, and the relationship between NAD+ availability and sirtuin activity, PARP activity, mitochondrial function, and circadian clock gene regulation is an active area of ageing research. Research models investigate how modulation of NAD+ levels — through supplementation, inhibition of NAD+-consuming enzymes like CD38, or enhancement of biosynthesis — affects endpoints including mitochondrial biogenesis, DNA repair efficiency, and gene expression of metabolic regulators.

NAD+ is hygroscopic and susceptible to hydrolysis, particularly at alkaline pH. Lyophilised powder should be stored at -20°C in a sealed, desiccated container. Stock solutions should be prepared in slightly acidic buffer (pH 6-7) and stored at -80°C in single-use aliquots. Researchers should verify NAD+ concentration by UV absorbance at 340 nm in the presence of alcohol dehydrogenase before use in quantitative enzymatic assays.

NAD+ as supplied by Elivena is a research-grade compound for use in controlled laboratory settings. It is not supplied as a dietary supplement or therapeutic product and is not approved for human administration outside of formally regulated contexts.